Preparation and radiolabeling of surface-modified magnetic nanoparticles with technetium-99m as potential radiopharmaceuticals in nuclear medicine.
Jul 29, 2014· Introduction. Non-Hodgkin's Lymphoma (NHL) also known as B and T cell lymphoma is a form of blood cancer originating in lymphatic system. Many investigations for treatment of NHL have been based on the development of antibody against CD-20 antigens which are expressed on the surface of B-cells [].Results of these investigations have led …
Jul 31, 2012· Radiolabeling efficiency of guanine coupling MNPs. The chelation efficiency of [99m Tc(H 2 O) 3 (CO) 3] + was 95 ± 2 % as analyzed by TLRC and HPLRC. In order …
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Preparation and radiolabeling of surface-modified magnetic nanoparticles with technetium-99m as potential radiopharmaceuticals in nuclear medicine. No Thumbnail. Authors Vukadinović, Aleksandar Janković, Drina Mirković, M Radović, Magdalena Perić, Marko R. Milanović, Zorana
Radiolabeling, in combination with immunochemical procedures, facilitates the rapid molecular identification of individual membrane proteins. ... Cell surface radioiodination has identified the molecular properties of B and T cell receptors of antigen, major histocompatibility complex glycoproteins and differentiation antigens. ... Preparation ...
Semantic Scholar extracted view of "Preparation and 68Ga‐radiolabeling of porous zirconia nanoparticle platform for PET/CT‐imaging guided drug delivery" by A. Polyák et al.
Jun 01, 2004· Preparation and radiolabeling of surface-modified magnetic nanoparticles with rhenium-188 for magnetic targeted radiotherapy ...
After surface modification with an amino silane coupling agent, N-[3-(trimethyoxysilyl) propyl]-ethylenediamine (SG-Si900), histidine was covalently linked to the amine group using glutaraldehyde as cross-linker. The magnetic nanoparticles were then radiolabeled with 1 8 8 Re with a labeling yield of 91.4+/-0.3% and good stability in vitro.
@article{Cao2004PreparationAR, title={Preparation and radiolabeling of surface-modified magnetic nanoparticles with rhenium-188 for magnetic targeted …
Jul 31, 2012· Cao J, Wang Y, Yu J, Xia J, Zhang C, Yin D et al (2004) Preparation and radiolabeling of surface-modified magnetic nanoparticles with rhenium-188 for magnetic targeted radiotherapy. J Magn Magn Mater 277:165–174. Article CAS Google Scholar Cao H, Gan J, Wang S, Xuan S, Wu Q, Li C et al (2007) Novel silica-coated iron–carbon …
Preparation and radiolabeling of surface-modified magnetic nanoparticles with technetium-99m as potential radiopharmaceuticals in nuclear medicine: en: dc.type: conferenceObject: en: dc.rights.license: ARR: dcterms.abstract
Niosomes were radiolabeled by surface chelation with reduced 99m Tc. Parameters affecting the radiolabeling efficiency such as concentration of stannous chloride (SnCl 2 ·H 2 O), pH, and incubation time were evaluated. In vitro stability of radiolabeled niosomes was studied in 0.9% saline and human serum at 37°C for up to 8 hours.
Early diagnosis of bone metastases is crucial to prevent skeletal-related events, and for that, the non-invasive techniques to diagnose bone metastases that make use of image-guided radiopharmaceuticals are being employed as an alternative to traditional biopsies. Hence, in the present work, we tested the efficacy of a gallium-68 (68Ga)-based compound as a …
Mar 01, 2003· Preparation and radiolabeling of antimony sulfide nanocolloids with two different particle sizes. ... Diff erences in surface characteristics of the colloids may account for these observations [6
DOTA was successfully adsorbed onto the surface of nanoparticles, while the 68Ga-radiolabeling method proved to be simple and effective. In the course of biodistribution studies, the 68Ga-labeled DOTA-ZrNPs showed proper radiolabeling stability in their original suspension and in blood serum. Pet/CT imaging studies confirmed a ...
Preparation and radiolabeling of surface-modified magnetic nanoparticles with technetium-99m as potential radiopharmaceuticals in nuclear medicine. No Thumbnail. …
Aug 01, 2012· The aim of this study was to develop a dual-modality PET/MR imaging probe by radiolabeling iron oxide magnetic nanoparticles (IONPs), surface functionalized with water soluble stabilizer 2,3 ...
Dec 13, 2021· Another category of radiolabeling uses derivatization strategy, in which non-radioactive NMs are synthesized first, and then radionuclide is conjugated to the surface of the pristine NMs by physical (e.g., adsorption) or chemical (typically via a radionuclide chelator anchored on the NMs surface) means.
Jul 29, 2014· Preparation and quality control of radionuclides. 111 In as 111 InCl 3 solution with a specific activity of higher than1.55 GBq/μg indium at time of calibration was obtained by a non-carrier-added method. Quality control of the radionuclidic[] showed the presence of 171 and 245 keV gamma energies, originating from 111 In and a purity of higher than %99.
Jul 29, 2014· 111 In and 90 Y with high radiochemical and radionuclide purity were prepared by 112 Cd (p,2n) 111 In nuclear reaction and a locally developed 90 Sr/ 90 Y generator, respectively. DOTA-rituximab immunoconjugates were prepared by the reaction of solutions of p-SCN-Bz-DOTA and rituximab in carbonate buffer (pH = 9.5) and the …
Jun 09, 2020· The preparation of NODAGA-pamidronic acid was performed via the N-Hydroxysuccinimide (NHS) ester strategy and was characterized using liquid chromatography-mass spectrometry ... The radiolabeling condition was found to be most optimum at a pH ranging from 4 to 4.5 and a temperature of above 60 °C. From previous …
Jun 09, 2020· Early diagnosis of bone metastases is crucial to prevent skeletal-related events, and for that, the non-invasive techniques to diagnose bone metastases that make use of image-guided radiopharmaceuticals are being employed as an alternative to traditional biopsies. Hence, in the present work, we tested the efficacy of a gallium-68 …
1 · Getting the substrate ready. Adding a coating to a damaged substrate might cause flaws in the floor coverings to be mirrored, destroying the aesthetic and function of the completed floor. Before applying the coatings, use an appropriate water or liquid primer to help avoid bond failure. Concrete surface preparation methods include diamond ...
Preparation and radiolabeling of surface-modified magnetic nanoparticles with technetium-99m as potential radiopharmaceuticals in nuclear medicine. Nema prikaza. …
In this paper, we describe the preparation of human serum albumin-coated magnetic particles of about 200 nm in diameter with narrow size distribution radiolabeled with 188Re for the purpose of magnetically targeted therapy. The optimum radiolabeling conditions are: SnCl2 x 2H2O 8 mg/ml, citric acid …
Sep 23, 2009· The present study describes for the first time a procedure for the radiolabeling of fullerene (C(60)) nanocrystals (nanoC(60)) with Na (125)I, as well as the biodistribution of radiolabeled nanoC(60) ((125)I-nanoC(60)). The solvent exchange method with tetrahydrofuran was used to make colloidal water suspensions of radiolabeled …
@article{Cao2004PreparationAR, title={Preparation and radiolabeling of surface-modified magnetic nanoparticles with rhenium-188 for magnetic targeted radiotherapy}, author={Jinquan Cao and Yongxian Wang and Junfeng Yu and Jiao-yun Xia and Chunfu Zhang and Duanzhi Yin and Urs O. H{"a}feli}, journal={Journal of Magnetism and …
Jun 09, 2020· The radiolabeling condition was found to be most optimum at a pH ranging from 4 to 4.5 and a temperature of above 60 °C. From previous work, we found that the pamidronic acid itself has a good bone binding affinity.
Corpus ID: 146054389; Preparation and radiolabeling of surface-modified magnetic nanoparticles with technetium-99m as potential radiopharmaceuticals in nuclear medicine
May 26, 2018· The core concept of radionanomedicine relies on efficient and reliable radiolabeling methods, to bind appropriate isotope with well-functionalized nanoparticles (NPs), and the use of tracer amounts of radiolabeled NPs. In this chapter, we focused on the three issues of producing radiolabeled NPs: choosing appropriate radionuclides for …
A new derivative (1) of diethylenetriamine pentaacetic acid (DTPA) is described. Compound 1 contains a hydrophobic unit (a triphenyl methyl group) and a hydrophilic unit (a DTPA ester), and therefore behaves as an amphiphile in aqueous solution.
Table 1 The average numbers of rhenium labeled to the magnetoferritin and histidine immobilized magnetoferritin samples that were calcutated over three experiments (N= 3) from size exclusion chromatography (SEC) results using protein and rhenium amounts in the collected fractions that are shown with straight line on the chromatograms. - …
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